Open AccessDEVELOPMENT OF A COMPOSITE OF POLY-Ɛ-CAPROLACTONE-CERIUM OXIDE
Author(s) -
Alejandra Melissa,
Simón Yobanny
Publication year - 2017
Publication title -
international journal of research - granthaalayah
Language(s) - English
Resource type - Journals
eISSN - 2394-3629
pISSN - 2350-0530
DOI - 10.29121/granthaalayah.v5.i7.2017.2158
Subject(s) - caprolactone , thermogravimetric analysis , differential scanning calorimetry , cerium oxide , electrospinning , materials science , biocompatibility , nanomaterials , chemical engineering , cerium , scanning electron microscope , composite number , polymer , composite material , oxide , nanotechnology , polymerization , metallurgy , physics , engineering , thermodynamics
Nanotechnology is used in a variety of sectors for the manufacture of materials. However, there is a risk from exposure to nanomaterials due to their chemical composition and processing form, giving rise to health risks. CeO2 particles present antioxidant properties that accelerate the wound poly-Ɛ-caprolactone (PCL) provides the property of biocompatibility and biodegradability of the material. For the regulation of the transport and release of cerium oxide particles was incorporated into a polymeric matrix composed of PCL. Therefore, in this study we propose the elaboration of a composite material of poly-Ɛ-caprolactone-cerium by the electrospinning technique. Electrospinning for example has been widely used to fabricate scaffolds imitating the structure of natural extracellular matrix. The fibers obtained with an average diameter of 600 nm was characterized by confocal microscopy, scanning electron microscopy, infrared spectroscopy, Differential thermal analysis, Thermogravimetric Analysis and Differential Scanning Calorimetry. Additionally, genotoxic effect was evaluated by comet assay in Vicia faba cell nuclei, results show that the material made has no genotoxic effects in Vicia faba cells.