Open AccessINFγ, TNFα, IL-6 LEVELS IN THE PERIPHERAL BLOOD SERUM IN DIFFERENT CLINICAL COURSES OF NONSPECIFIC VULVOVAGINITIS IN ADOLESCENT GIRLS
Author(s) -
Smailova Lazat Kenzhebekovna,
Bilalova Gulshat Tursunovna,
Kurmanova Almagul Medeubaeva
Publication year - 2017
Publication title -
international journal of research - granthaalayah
Language(s) - English
Resource type - Journals
eISSN - 2394-3629
pISSN - 2350-0530
DOI - 10.29121/granthaalayah.v5.i7.2017.2147
Subject(s) - pathological , immunology , cytokine , immunity , peripheral blood , humoral immunity , medicine , tumor necrosis factor alpha , disease , inflammation , immune system
The conducted study showed that increased production of anti-inflammatory INFγ cytokine is observed in girls and adolescents with acute nonspecific vulvovaginitis compared to the subacute course of the disease, though no adequately high production of this cytokine is practically observed in both cases. The obtained data indicate the suppression of both the cell and humoral anti-inflammatory immunity. IL-6 is responsible for the specificity and the adequacy of immunological reactions. This fact is connected primarily with the presence of multidirectional pathological changes in the immunity system.