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"One pot" Microwave Assisted Synthesis of 5,10,15-Tri(4-Methoxyphenyl)- 20-( 4-Chlorophentyl)-21H,23H-Porphyrin and its Zinc (II) Complex.
Author(s) -
Erika Lilián Loredo Calderón,
Carolina Martínez Lejia,
Susana López Cortina,
Blanca Flores,
Eugenio Hernández Fernández,
Víctor M. Jiménez Pérez,
Erick Cuevas Yáñez
Publication year - 2012
Publication title -
química hoy chemistry sciences
Language(s) - English
Resource type - Journals
ISSN - 2007-1183
DOI - 10.29105/qh2.2-136
Subject(s) - porphyrin , zinc , molecule , photodynamic therapy , chemistry , combinatorial chemistry , microwave , stereochemistry , photochemistry , medicinal chemistry , organic chemistry , physics , quantum mechanics
Toe synthesis of new unsymmetrical A,B porphyrin, 5,10,15-tri(4-methoxyphenyl)-20-(4-chlorophenyl)-21H, 23H-porphyrin, 1, and its Zinc(II) complex, 5, 1 O, 15-tri( 4-methoxyphenyl)-20-( 4-chlorophenyl)-21, 23- Zinc(II)-porphine, l, was accomplished using both conventional and "one pot" solventless microwave assisted methods with interesting comparative results. The obtained molecules were characterized by 'H NMR, UV-Vis and MS. These molecules are considered to represent new compounds with potential application as photosensitizers in photodynamic therapy.

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