Open AccessHistopathological changes of some internal organs in broilers fed T-2 Toxin
Author(s) -
K K Shereen
Publication year - 2012
Publication title -
maǧallaẗ al-qādisiyyaẗ li-ʻulūm al-ṭibb al-bayṭarī
Language(s) - English
Resource type - Journals
eISSN - 2313-4429
pISSN - 1818-5746
DOI - 10.29079/vol11iss2art192
Subject(s) - bursa of fabricius , toxin , biology , lymphatic system , broiler , spleen , kidney , physiology , small intestine , medicine , endocrinology , zoology , immunology , microbiology and biotechnology
Forty, one-day-old male broiler chicks (Ross 308), were randomly distributed at one day of age to 2 experimental groups consisting of 10 birds with two replicates for 35 days. Group 1 fed control diet with no T-2 toxin (negative control),while group 2 fed T-2 toxin contaminated diet at a rate of 4 ppm. Scarifying birds done at the end of the experiment, bursa of Fabricius, spleen, liver, kidney and intestine, were sectioned for microscopical examination . Results showed that T-2 toxin, was hepatotoxic, nephrotoxic, toxic to lymphatic tissue, haemopoetic tissue, and gastrointestinal tissues. And these organs are considered to be the target organs for T-2 toxin which primarily affected during T-2 toxicosis.