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Estimation of Some Hematological Parameters, Liver Enzymes and Iron Mineral in Adult of Celiac Disease Patients
Author(s) -
Sahab K. Shakir
Publication year - 2021
Publication title -
basrah journal of science
Language(s) - English
Resource type - Journals
eISSN - 2664-8296
pISSN - 2664-8288
DOI - 10.29072/basjs.2021310
Subject(s) - medicine , gastroenterology , malabsorption , hemoglobin , erythrocyte sedimentation rate , gluten , anemia , disease , alkaline phosphatase , enzyme , pathology , biology , biochemistry
Celiac disease is one of the most prevalent chronic illnesses. It is produced due to gluten, a protein found in wheat, rye, and barley that damages the villi, so the body cannotadequately absorb nutrients. This s tudy was undertaken to determine of some hematological parameters, liver enzyme and iron (Fe) in celiac disease patients compared with the healthy group. The results indicated a high significantly increase (p ≤ 0.01) in levels of ALT (alanine transferase), ALP (alkaline phosphatase), ESR (erythrocyte sedimentation rate), AST (aspartate transferase) in age category (41-60) and WBC (white blood cells) in age category (41-60), while significantly increased (p ≤ 0.05) in levels of AST and WBC in age category (20-40) in celiac disease patients as compared with healthy group. High significantly decreased (p ≤ 0.01) in levels of hemoglobin in age category (20-40), RBC (red blood cells) and Fe, while levels of hemoglobin in age category (41-60) was significantly decreased (p ≤ 0.05) in celiac disease patients as compared with healthy group. In celiac disease patients of age category (20-40) as compared with age category (41-60), there was a high significant difference (p ≤ 0.01) in ESR, AST and Fe and significant difference (p ≤ 0.05) in ALT and ALP, while no significant in hemoglobin, RBC and WBC in celiac disease patients of age category (20-40) as compared with age category (41-60). This study concludes that untreated celiac disease causes nutrient deficiencies due to malabsorption, which causes anemia, inflammations, and elevated liver enzymes.

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