Open AccessRelevance of new scientific information (Santos‐Vigil et al., 2018 ) in relation to the risk assessment of genetically modified crops with Cry1Ac
Author(s) -
Dumont Antonio Fernandez,
Lanzoni Anna,
Waigmann Elisabeth,
Paoletti Claudia
Publication year - 2018
Publication title -
efsa supporting publications
Language(s) - English
Resource type - Journals
ISSN - 2397-8325
DOI - 10.2903/sp.efsa.2019.en-1504
Subject(s) - cry1ac , risk assessment , genetically modified crops , agricultural science , microbiology and biotechnology , biology , computer science , transgene , genetics , computer security , gene
Following a request from the European Commission, EFSA assessed the scientific publication by Santos‐Vigil et al. (2018). The outstanding question was whether or not the new scientific information contains elements that could lead the EFSA GMO Panel to reconsider the outcome of its previous risk assessments on genetically modified crops expressing Cry1Ac protein. Santos‐Vigil et al. (2018) investigated the allergenic potential and immunological effects of the Cry1Ac protein and compared it with ovalbumin after intragastric administration to BALB/c mice, using a specific model of food‐allergy. Shortcomings in the study design and data interpretation limit the possibility to attribute findings to the intrinsic properties of the Cry1Ac protein. The publication by Santos‐Vigil et al. (2018) does not bring new elements that would lead the EFSA GMO Panel to reconsider the outcome of its previous scientific opinions on genetically modified crops with Cry1Ac. Therefore, EFSA considers that the previous risk assessment conclusions on GM crops with Cry1Ac remain valid and applicable.