Open AccessEFSA Scientific Colloquium 24 – 'omics in risk assessment: state of the art and next steps
Author(s) -
Aguilera Jaime,
AguileraGomez Margarita,
Barrucci Federica,
Cocconcelli Pier Sandro,
Davies Howard,
Denslow Nancy,
Lou Dorne Jean,
Grohmann Lutz,
Herman Lieve,
Hogstrand Christer,
Kass George E. N.,
Kille Peter,
Kleter Gijs,
Nogué Fabien,
Plant Nick J.,
Ramon Matthew,
Schoonjans Reinhilde,
Waigmann Elisabeth,
Wright Matthew C.
Publication year - 2018
Publication title -
efsa supporting publications
Language(s) - English
Resource type - Journals
ISSN - 2397-8325
DOI - 10.2903/sp.efsa.2018.en-1512
Subject(s) - omics , risk assessment , data science , genomics , computer science , microbiology and biotechnology , biology , bioinformatics , genome , biochemistry , computer security , gene
In recent years, the development of innovative tools in genomics, transcriptomics, proteomics and metabolomics (designated collectively as 'omics technologies) has opened up new possibilities for applications in scientific research and led to the availability of vast amounts of analytical data. The interpretation and integration of 'omics data can provide valuable information on the functional status of an organism and on the effect of external factors such as stressors. The European Food Safety Authority's (EFSA) 24th Scientific Colloquium on 'omics in risk assessment: state of the art and next steps explored the opportunities for integration of datasets produced via specific 'omics tools within the remit of EFSA's risk assessment approaches and tried to build further towards concrete paths of implementation. Discussions focused on genomics in microbial strain characterisation, metabolomics for the comparative assessment of GM plants and the use of 'omics for toxicological and environmental risk assessment. From the Colloquium it became clear that 'omics technologies are a valuable addition in some aspects of risk assessment of food and feed products and the environment, especially now that this technology is almost mature and stable. However, a consistent reporting framework for data collection, processing, interpretation, storage and curation should be further drawn up together with national and international organisations before 'omics technologies can be routinely used in risk assessment. For 'omics datasets in chemical and environmental risk assessments, the use of 'omics technologies alongside current toxicological or environmental risk assessment approaches is needed to re‐inforce confidence and expertise before implementation of these datasets as a standalone tool in risk assessment. Test cases could be worked out to enhance confidence in the use of 'omics datasets in risk assessment.