Open AccessAssessment of genetically modified maize MON 89034 × 1507 × MIR162 × NK603 × DAS ‐40278‐9 for food and feed uses, under regulation ( EC ) No 1829/2003 (application EFSA‐GMO‐NL ‐2018‐151)
Author(s) -
Mullins Ewen,
Bresson JeanLouis,
Dalmay Tamas,
Dewhurst Ian Crawford,
Epstein Michelle M,
Firbank Leslie George,
Guerche Philippe,
Hejatko Jan,
Naegeli Hanspeter,
Moreno Francisco Javier,
Nogué Fabien,
Rostoks Nils,
Sánchez Serrano Jose Juan,
Savoini Giovanni,
Veromann Eve,
Veronesi Fabio,
Ardizzone Michele,
De Sanctis Giacomo,
Dumont Antonio Fernandez,
Federici Silvia,
Gennaro Andrea,
Gomez Ruiz Jose Angel,
Goumperis Tilemachos,
Kagkli Dafni Maria,
Lanzoni Anna,
Lenzi Paolo,
Lewandowska Aleksandra,
Neri Franco Maria,
Paraskevopoulos Konstantinos,
Raffaello Tommaso,
Streissl Franz
Publication year - 2022
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2022.7451
Subject(s) - genetically modified maize , zea mays , microbiology and biotechnology , environmental safety , genetically modified organism , biology , genetically modified crops , agronomy , transgene , medicine , human health , biochemistry , environmental health , gene
Genetically modified maize MON 89034 × 1507 × MIR162 × NK603 × DAS‐40278‐9 was developed by crossing to combine five single events: MON 89034, 1507, MIR162, NK603 and DAS‐40278‐9. The GMO Panel previously assessed the five single maize events and 16 of the subcombinations and did not identify safety concerns. No new data on the single maize events or the assessed subcombinations were identified that could lead to the modification of the original conclusions on their safety. The molecular characterisation, comparative analysis (agronomic, phenotypic and compositional characteristics) and the outcome of the toxicological, allergenicity and nutritional assessment indicate that the combination of the single maize events and of the newly expressed proteins in the five‐event stack maize does not give rise to food and feed safety and nutritional concerns. The GMO Panel concludes that five‐event stack maize, as described in this application, is as safe as the non‐GM comparator and non‐GM maize varieties tested. In the case of accidental release of viable five‐event stack maize grains into the environment, this would not raise environmental safety concerns. The GMO Panel assessed the likelihood of interactions among the single events in nine of the maize subcombinations not previously assessed and concludes that these are expected to be as safe as the single events, the previously assessed subcombinations and the five‐event stack maize. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize MON 89034 × 1507 × MIR162 × NK603 × DAS‐40278‐9. Post‐market monitoring of food/feed is not considered necessary. The GMO Panel concludes that the five‐event stack maize and its subcombinations are as safe as its non‐GM comparator and the tested non‐GM maize varieties with respect to potential effects on human and animal health and the environment.