Open AccessSafety and efficacy of an additive consisting of synthetic vitamin K 1 (phytomenadione) for horses ( JARAZ Enterprises GmbH & Co. KG )
Author(s) -
Bampidis Vasileios,
Azimonti Giovanna,
Bastos Maria de Lourdes,
Christensen Henrik,
Dusemund Birgit,
Fašmon Durjava Mojca,
Kouba Maryline,
LópezAlonso Marta,
López Puente Secundino,
Marcon Francesca,
Mayo Baltasar,
Pechová Alena,
Petkova Mariana,
Ramos Fernando,
Sanz Yolanda,
Villa Roberto Edoardo,
Woutersen Ruud,
Groop Jürgen,
Anguita Montserrat,
Galobart Jaume,
Holczknecht Orsolya,
Manini Paola,
Pettenati Elisa,
Pizzo Fabiola,
TarrésCall Jordi
Publication year - 2021
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2021.6538
Subject(s) - european commission , vitamin , feed additive , food additive , medicine , animal feed , food science , microbiology and biotechnology , vitamin e , european union , business , chemistry , biology , biochemistry , antioxidant , broiler , economic policy
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed ( FEEDAP ) was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of vitamin K 1 (phytomenadione) produced by chemical synthesis when used as a nutritional additive in complementary feed of horses at a maximum supplemental level of 14 mg vitamin K 1 /horse per day. The use of vitamin K1 is safe when used as a feed additive for horses under the proposed conditions of use. The use of vitamin K1 in nutrition of horses under the proposed conditions of use is considered safe for the consumer and the environment. No exposure of users by inhalation is expected. The Panel cannot conclude on the potential of the additive to be a skin and eye irritant. Vitamin K1 is considered a moderate dermal sensitiser. Vitamin K1 is an effective source of vitamin K in horse nutrition. The Panel recommends that the specifications of the additive refer to the substance‐related impurities listed in the most updated monograph of the European Pharmacopoeia.