Open AccessReasoned opinion on the toxicological properties and maximum residue levels for propoxur
Author(s) -
Anastassiadou Maria,
Bernasconi Giovanni,
Brancato Alba,
Carrasco Cabrera Luis,
Ferreira Lucien,
Greco Luna,
Jarrah Samira,
Kazocina Aija,
Leuschner Renata,
Magrans Jose Oriol,
Miron Ileana,
Nave Stefanie,
Pedersen Ragnor,
Reich Hermine,
Rojas Alejandro,
Sacchi Angela,
Santos Miguel,
Scarlato Alessia Pia,
Theobald Anne,
Vagenende Benedicte,
Verani Alessia
Publication year - 2021
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2021.6374
Subject(s) - propoxur , member states , european commission , reference values , risk assessment , european union , environmental health , toxicology , business , pesticide , biology , medicine , computer science , agronomy , economic policy , computer security
In accordance with Article 43 of Regulation ( EC ) No 396/2005, the European Commission requested EFSA to prepare a reasoned opinion on the toxicological properties and the existing maximum residue levels ( MRL s) set for propoxur. EFSA was requested to assess the toxicological properties of propoxur and derive toxicological reference values, based on the toxicological assessment performed by Health Canada. EFSA was also requested to review the information provided by Member States and the UK on the metabolism of propoxur in plants and animals and on the current MRL s, as well as the limit of quantification ( LOQ ) that can be achieved with analytical methods used in MRL enforcement. Based on the information available to EFSA , toxicological reference values could not be derived for propoxur. No evidence was provided by Member States and UK that the existing EU MRL s need to be maintained as import tolerances. Information to support the current MRL s or alternative MRL s have not been provided by Member States and the UK . Codex MRL s are not in place. EFSA therefore recommended lowering of all existing EU MRL s for propoxur to the LOQ . According to the EU Reference Laboratories, sufficiently validated analytical methods are available to analyse for propoxur residues in all plant and animal commodities. Lacking toxicological reference values derived at EU level, a conclusion cannot be derived whether the setting of MRL s at the LOQ s is sufficiently protective for the European consumers.