Open AccessSafety and efficacy of OptiPhos ® PLUS (6 phytase) for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding
Author(s) -
Bampidis Vasileios,
Azimonti Giovanna,
Bastos Maria de Lourdes,
Christensen Henrik,
Dusemund Birgit,
Kos Durjava Mojca,
Kouba Maryline,
LópezAlonso Marta,
López Puente Secundino,
Marcon Francesca,
Mayo Baltasar,
Pechová Alena,
Petkova Mariana,
Ramos Fernando,
Sanz Yolanda,
Villa Roberto Edoardo,
Woutersen Ruud,
Cocconcelli Pier Sandro,
Dierick Noël,
Glandorf Boet,
Herman Lieve,
Maradona Prieto Miguel,
Martelli Giovanna,
Saarela Maria,
Anguita Montserrat,
Galobart Jaume,
Holczknecht Orsolya,
Manini Paola,
Pettenati Elisa,
TarrésCall Jordi,
Pizzo Fabiola
Publication year - 2020
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2020.6161
Subject(s) - biology , phytase , feed additive , animal feed , microbiology and biotechnology , zoology , genetically modified organism , selective breeding , veterinary medicine , animal breeding , broiler , ecology , medicine , biochemistry , gene , enzyme
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed ( FEEDAP ) was asked to deliver a scientific opinion on the safety and efficacy of OptiPhos PLUS ® , intended to be used as a feed additive for laying hens, turkeys for breeding, chickens for breeding, minor poultry species for egg production purposes and breeding. The active substance is 6‐phytase produced by a genetically modified strain of Komagataella phaffii . The EFSA FEEDAP Panel concluded that the genetic modification of the production strain does not give rise to safety concerns. Based on the tolerance studies provided, the Panel concluded that the additive is safe for the target species under the conditions of use with a wide margin of safety. The additive was considered safe also for the consumer and the environment. The additive is not a skin irritant but is a dermal sensitiser. The FEEDAP Panel could not conclude on the eye irritation potential of the additive. Owing to the proteinaceous nature of the active substance, the additive is considered a respiratory sensitiser. The FEEDAP Panel concluded that the additive has the potential to be efficacious in increasing the phosphorus utilisation in laying hens at the level of 250 FTU /kg feed. These conclusions were extended to turkeys for breeding and chickens for breeding and extrapolated to minor poultry species for egg production purposes and breeding.