Open AccessReview of the existing maximum residue levels for clethodim according to Article 12 of Regulation ( EC ) No 396/2005
Author(s) -
Anastassiadou Maria,
Brancato Alba,
Carrasco Cabrera Luis,
Ferreira Lucien,
Greco Luna,
Jarrah Samira,
Kazocina Aija,
Leuschner Renata,
Magrans Jose Oriol,
Miron Ileana,
Pedersen Ragnor,
Raczyk Marianna,
Reich Hermine,
Ruocco Silvia,
Sacchi Angela,
Santos Miguel,
Stanek Alois,
Tarazona Jose,
Theobald Anne,
Verani Alessia
Publication year - 2019
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2019.5706
Subject(s) - european commission , risk assessment , residue (chemistry) , member states , european union , pesticide residue , metabolite , veterinary drug , toxicology , pesticide , business , chemistry , biology , agronomy , computer science , biochemistry , computer security , economic policy , chromatography
According to Article 12 of Regulation ( EC ) No 396/2005, EFSA has reviewed the maximum residue levels ( MRL s) currently established at European level for the pesticide active substance clethodim. To assess the occurrence of clethodim residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/ EEC , the MRL s established by the Codex Alimentarius Commission and European authorisations reported by Member States (including the supporting residues data). Based on the assessment of the available data, MRL could not be proposed because an overall consumer risk assessment could not be finalised. Risk managers should be made aware that the genotoxic potential of the clethodim metabolite 3‐chloroallyl alcohol, the aglycon of 3‐chlorolallyl alcohol glucoside (M14A/M15A) could not be concluded and no toxicological reference values could be derived for this metabolite. Until a conclusion on the toxicological properties of the metabolite is reached, a decision on the residue definition for risk assessment cannot be made which is a prerequisite to perform a reliable dietary risk assessment.