Open AccessAssessment of genetically modified maize Bt11 x MIR162 x 1507 x GA21 and three subcombinations independently of their origin, for food and feed uses under Regulation ( EC ) No 1829/2003 (application EFSA ‐ GMO ‐ DE ‐2010‐86)
Author(s) -
Naegeli Hanspeter,
Birch Andrew Nicholas,
Casacuberta Josep,
De Schrijver Adinda,
Gralak Mikołaj Antoni,
Guerche Philippe,
Jones Huw,
Manachini Barbara,
Messéan Antoine,
Nielsen Elsa Ebbesen,
Nogué Fabien,
Robaglia Christophe,
Rostoks Nils,
Sweet Jeremy,
Tebbe Christoph,
Visioli Francesco,
Ardizzone Michele,
Federici Silvia,
Fernandez Dumont Antonio,
Gennaro Andrea,
Gómez Ruiz Jose Ángel,
Lanzoni Anna,
Neri Franco Maria,
Papadopoulou Nikoletta,
Paraskevopoulos Konstantinos
Publication year - 2018
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2018.5309
Subject(s) - context (archaeology) , genetically modified maize , microbiology and biotechnology , agricultural science , biology , zea mays , food science , agronomy , genetically modified crops , transgene , genetics , paleontology , gene
In this opinion, the GMO Panel assessed the four‐event stack maize Bt11 × MIR 162 × 1507 × GA 21 and three of its subcombinations, independently of their origin. The GMO Panel previously assessed the four single events and seven of their combinations and did not identify safety concerns. No new data on the single events or the seven subcombinations leading to modification of the original conclusions were identified. Based on the molecular, agronomic, phenotypic and compositional characteristics, the combination of the single events in the four‐event stack maize did not give rise to food/feed safety issues. Based on the nutritional assessment of the compositional characteristics of maize Bt11 × MIR 162 × 1507 × GA 21, foods and feeds derived from the genetically modified ( GM ) maize are expected to have the same nutritional impact as those derived from non‐ GM maize varieties. In the case of accidental release of viable grains of maize Bt11 × MIR 162 × 1507 × GA 21 into the environment, this would not raise environmental safety concerns. The GMO Panel concludes that maize Bt11 × MIR 162 × 1507 × GA 21 is nutritionally equivalent to and as safe as its non‐ GM comparator in the context of the scope of this application. For the three subcombinations included in the scope, for which no experimental data were provided, the GMO Panel assessed the likelihood of interactions among the single events and concluded that their combinations would not raise safety concerns. These maize subcombinations are therefore expected to be as safe as the single events, the previously assessed subcombinations and the four‐event stack maize. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize Bt11 × MIR 162 × 1507 × GA 21 and its subcombinations. A minority opinion expressed by a GMO Panel member is appended to this opinion.