Open AccessSafety of cassia gum as a feed additive for dogs and cats based on a dossier submitted by Glycomer GmbH
Author(s) -
Rychen Guido,
Aquilina Gabriele,
Azimonti Giovanna,
Bampidis Vasileios,
Bastos Maria de Lourdes,
Bories Georges,
Chesson Andrew,
Cocconcelli Pier Sandro,
Flachowsky Gerhard,
Kolar Boris,
Kouba Maryline,
López Puente Secundino,
LópezAlonso Marta,
Mantovani Alberto,
Mayo Baltasar,
Ramos Fernando,
Saarela Maria,
Villa Roberto Edoardo,
Wallace Robert John,
Wester Pieter,
Lundebye AnneKatrine,
Nebbia Carlo,
Renshaw Derek,
Innocenti Matteo Lorenzo,
Gropp Jürgen
Publication year - 2017
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2017.4710
Subject(s) - cassia , food science , biology , traditional medicine , zoology , microbiology and biotechnology , medicine , alternative medicine , pathology , traditional chinese medicine
The additive cassia gum consists mainly of high‐molecular weight polysaccharides composed primarily of a linear chain of 1,4‐β‐ d ‐mannopyranose units with 1,6‐linked α‐ d ‐galactopyranose units. In 2014, the Panel on Additives and Products or Substances used in Animal Feed ( FEEDAP ) delivered an opinion on the safety and efficacy of cassia gum. The FEEDAP Panel concluded, based on positive findings observed in a bacterial reverse mutation test with a semirefined cassia gum (about 70 mg anthraquinones/kg) but not with purified semirefined cassia gum that meets the specification as a food additive (< 0.5 mg anthraquinones/kg), that only purified semirefined cassia gum that meets the specifications of cassia gum as a food additive can be considered safe for cats and dogs, at a maximum content of 1.5% cassia gum (15,000 mg/kg feed) in dry matter, corresponding to 1.32% (13,200 mg/kg feed) in a standardised complete feed with 12% water content. The FEEDAP Panel also concluded that cassia gum should be regarded as a skin and respiratory sensitiser and as a potential irritant to skin and eyes. Following this opinion, the European Commission gave the possibility to the applicant to submit complementary information on the safety for all animal species. No new data were submitted to address the potential of the additive to exert mutagenic effects, and therefore, the FEEDAP Panel is not in the position to modify the conclusions reached in the previous opinion.