Open AccessScientific Opinion on Flavouring Group Evaluation 207 (FGE.207): Consideration of genotoxic potential for one branched‐chain aliphatic acyclic α,β‐unsaturated 2‐alkylated aldehyde with additional double‐bonds, from subgroup 1.1.2 of FGE.19 and four alicyclic aldehydes with the α,β‐unsaturation in a side‐chain, from subgroup 2.1 of FGE.19, which are considered to be covered by the one substance of subgroup 1.1.2, by EFSA
Author(s) -
Efsa Publication
Publication year - 2013
Publication title -
efsa journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.076
H-Index - 97
ISSN - 1831-4732
DOI - 10.2903/j.efsa.2013.3228
Subject(s) - genotoxicity , chemistry , food additive , stereochemistry , organic chemistry , toxicity
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of one flavouring substance, 2,6‐dimethyl‐2, 5,7‐octatriene‐1‐ol acetate [FL‐no: 09.931], from subgroup 1.1.2 of FGE.19, which is considered to be representative for four substances, 12‐beta‐santalen‐14‐ol [FL‐no: 02.216], 12‐alpha‐santalen‐14‐ol [FL‐no: 02.217], santalyl acetate [FL‐no: 09.034] and santalyl phenylacetate [FL‐no: 09.712], from subgroup 2.1 of FGE.19. The Flavour Industry has provided genotoxicity studies for the representative substance 2,6‐dimethyl‐2, 5,7‐octatriene‐1‐ol acetate [FL‐no: 09.931] and these data are considered by EFSA to be representative for the four substances [FL‐no: 02.216, 02.217, 09.034 and 09.712]. Based on the new data, the Panel concluded that 2,6‐dimethyl‐2, 5,7‐octatriene‐1‐ol acetate [FL‐no: 09.931] from FGE.19 subgroup 1.1.2 does not give rise to concern with respect to genotoxicity and can accordingly be evaluated using the Procedure. This conclusion can also be applied to the four substances 12‐beta‐santalen‐14‐ol [FL‐no: 02.216], 12‐alpha‐santalen‐14‐ol [FL‐no: 02.217], santalyl acetate [FL‐no: 09.034] and santalyl phenylacetate [FL‐no: 09.712] from FGE.19 subgroup 2.1 for which 2,6‐dimethyl‐2, 5,7‐octatriene‐1‐ol acetate [FL‐no: 09.931] is representative.