Open AccessInfluência da Disbiose na Patologia do Couro Cabeludo
Author(s) -
Francisca Morgado,
Rui Oliveira Soares
Publication year - 2021
Publication title -
revista da sociedade portuguesa de dermatologia e venereologia
Language(s) - English
Resource type - Journals
eISSN - 2182-2409
pISSN - 2182-2395
DOI - 10.29021/spdv.79.4.1420
Subject(s) - alopecia areata , dermatology , dysbiosis , microbiome , medicine , psoriasis , scalp , vitiligo , seborrheic dermatitis , immunology , disease , pathology , bioinformatics , biology
In recent years, several studies have demonstrated the involvement of the intestinal microbiota in immune-mediated diseases such as diabetes, ulcerative colitis, and multiple sclerosis. There are few data on the follicular microbiome and its role in the pathogenesis of scalp diseases. Some studies show influence of dysbiosis on these diseases, and manipulation of the microbiome may represent a possible therapeu- tic option. This article reviews current knowledge regarding the impact of dysbiosis on dermatological diseases of the scalp, such as seborrheic dermatitis, psoriasis, alopecia areata, androgenetic alopecia, lichen planus pilaris, frontal fibrosing alopecia and decalvant folliculitis. A broader understanding of this may suggest additional treatments beyond conventional therapies.