Open AccessKaposi Sarcoma in Solid Organ Transplant Recipients: A challenging Case
Author(s) -
Daniela Macedo,
Pedro Garrido,
Isabel Fernandes,
Alice Santana,
J. Guerra,
João BorgesCosta
Publication year - 2019
Publication title -
revista da sociedade portuguesa de dermatologia e venereologia
Language(s) - English
Resource type - Journals
eISSN - 2182-2409
pISSN - 2182-2395
DOI - 10.29021/spdv.77.3.1085
Subject(s) - malignancy , sarcoma , medicine , incidence (geometry) , population , disease , refractory (planetary science) , renal transplant , epidemiology , intensive care medicine , transplantation , pathology , biology , environmental health , physics , astrobiology , optics
Kaposi sarcoma is a low-grade vascular tumor, associated with human herpesvirus-8 infection. Solid organ transplant recipients have a much higher risk of this malignancy, with estimated incidence rates increased 84 to 500 times. The risk is even higher in some ethnic groups, already with a higher incidence of this disease. We report a case of a 37-year-old African male, a kidney transplant recipient, with a Kaposi sarcoma refractory to different treatment options. The present case puts in evidence the challenges associated with the management of this disease in this high-risk population and highlights the role of a multidisciplinary approach to achieve effective treatment, particularly in advanced and refractory forms.