Open AccessFatal Orbital Pyoderma Gangrenosum with Central Nervous System Involvement
Author(s) -
Sofia Lopes,
Júlia Vide,
Sofia Magina,
Ana Paula Cunha,
Filomena Azevedo
Publication year - 2018
Publication title -
revista da sociedade portuguesa de dermatologia e venereologia
Language(s) - English
Resource type - Journals
eISSN - 2182-2409
pISSN - 2182-2395
DOI - 10.29021/spdv.76.4.952
Subject(s) - pyoderma gangrenosum , medicine , dermatology , central nervous system , pyoderma , head and neck , disease , surgery , pathology
Pyoderma gangrenosum is a chronic inflammatory disease characterized by the development of a painful deep ulcer with undermined borders. Head and neck are rarely affected regions of the body and also usually associated with a worse prognosis. Corticosteroids are the mainstay of treatment although available options are not specific nor completely effective in pyoderma gangrenosum. We report the case of a 46-year-old patient with an aggressive orbital pyoderma gangrenosum with progressive extension to the central nervous system and insufficient response to treatment, ultimately leading to patient’s death.