Open AccessClinical significance of 24-hour blood pressure monitoring in prediction of hypertension development in patients with gout
Author(s) -
М. В. Губанова,
Н. Н. Кушнаренко,
Т. М. Караваева
Publication year - 2021
Publication title -
sibirskij žurnal kliničeskoj i èksperimentalʹnoj mediciny
Language(s) - English
Resource type - Journals
eISSN - 2713-2927
pISSN - 2713-265X
DOI - 10.29001/2073-8552-2021-36-3-104-110
Subject(s) - medicine , blood pressure , gout , pulse pressure , diastole , mean blood pressure , heart rate
Aim. The aim of the study was to develop the model for establishing early diagnosis of hypertension in patients with gout. The model was based on data of 24-hour blood pressure monitoring. Material and Methods. A total of 69 patients with gout were enrolled in a single-stage cross-sectional prospective study. Three study groups were assigned as follows: group 1 (main group) comprised hypertensive men with gout (n = 41); group 2 (comparison group) comprised normotensive men with gout (n = 28); group 3 (control) included relatively healthy men (n = 30). Daily blood pressure monitoring was performed on an outpatient basis using a BPLab device (Peter Telegin, Russia). Results . The significant intergroup differences were found in the following parameters: lowest, mean, and highest 24-hour systolic blood pressure (SBP) values in patients of main and comparison groups (р 0.54, then the hypertension development was predicted in gout patients. The sensitivity of developed diagnostic model was 0.84, and the specificity was 0.95. Conclusion. Тhe proposed model, based on the assessment of average-daily values of the lowest, mean, and highest SBP, allowed to establish early diagnosis of hypertension in patients with gout with the accuracy of up to 90%.