Open AccessThe role of inflammation in the development of metabolic disorders in patients with arterial hypertension
Author(s) -
Лариса Владимировна Журавлева,
Марія Валеріївна Кулікова
Publication year - 2019
Publication title -
sibirskij medicinskij žurnal
Language(s) - English
Resource type - Journals
ISSN - 2073-8552
DOI - 10.29001/2073-8552-2019-34-3-45-52
Subject(s) - inflammation , medicine , diabetes mellitus , pathogenesis , metabolic syndrome , type 2 diabetes mellitus , type 2 diabetes , immune system , bioinformatics , intensive care medicine , immunology , endocrinology , biology
In recent years, the comorbid course of cardiovascular diseases, primarily arterial hypertension with impaired carbohydrate tolerance or type 2 diabetes mellitus, is becoming increasingly important in the developed countries of the world. In this regard, the need for a more detailed study of the general mechanisms of the development of arterial hypertension, pre-diabetes, and type 2 diabetes mellitus, namely inflammation, is increasing. There are many studies that investigate the role of inflammation in hypertension and associated glucometabolic disorders, but the exact mechanisms by which activated immune cells lead to the development and maintenance of these conditions remain to be seen. Obtaining new data in this area may contribute to a deeper understanding of cardiometabolic disorder pathogenesis. It may allow to predict the progression of these disorders at the early stages and to develop effective preventive and therapeutic tactics for their correction.