Open AccessCOMPARATIVE ANALYSIS OF DEMOGRAPHIC, ANAMNESTIC, CLINICAL-LABORATORY AND INSTRUMENTAL DATA IN PATIENTS WITH MYOCARDIAL INFARCTION WITH AND WITHOUT OBSTRUCTIVE LESION OF CORONARY ARTERIES
Author(s) -
С. В. Кручинова,
Е. Д. Космачева,
В. А. Порханов
Publication year - 2019
Publication title -
sibirskij medicinskij žurnal
Language(s) - English
Resource type - Journals
ISSN - 2073-8552
DOI - 10.29001/2073-8552-2018-33-4-69-75
Subject(s) - medicine , myocardial infarction , cardiology , coronary arteries , coronary artery disease , lesion , infarction , artery , surgery
Objective : to give a comparative characterization of myocardial infarction with and without obstructive lesion of coronary arteries. Material and Methods . The study involved 4639 patients included in the first total register of acute coronary syndrome in the Krasnodar Territory for the first 12 months of register operation. A comparative analysis of patients with myocardial infarction with obstructive lesion and without obstructive lesion of coronary arteries was performed. Results . Between November 2016 and November 2017, 4453 patients with myocardial infarction with obstructive coronary disease, including 2261 men (50.8%) and 2192 women (49.2%) were enrolled in the register. The mean age of patients was 68.3±12.03 years (69.3±3.42 years in men; 63.4±7.35 years in women). The criteria for myocardial infarction without obstructive coronary artery disease were present in 186 people (4.1%), including 72 men (38.7%) and 114 women (72.3%). The average age of the patients was 54.2±4.53 years; age of men with myocardial infarction without obstructive coronary disease was 56.3±3.52 years; age of women was 52.1±3.12 years. The article presents a detailed comparative analysis of demographic, medical history, clinical-instrumental, and laboratory data of these patient groups. Conclusion . Compared with patients who had obstructive coronary changes, the cohort of patients with myocardial infarction without obstructive lesions of the coronary arteries was younger and included more female patients; among the risk factors in this group, smoking and arterial hypertension were significant; the rates of newly diagnosed diabetes mellitus and Q-positive myocardial infarction were higher. According to the analysis of echocardiographic data, significant decrease in global contractility of the left ventricular myocardium was less common; analysis of laboratory data showed that patients more often had low platelet count.