Open AccessPerioperative hyperbaric oxygen treatment and postoperative complications following secondary breast reconstruction after radiotherapy: a case-control study of 45 patients
Author(s) -
Eva L Meier,
Stefan Hummelink,
Nina Lansdorp,
O.W.A. Boonstra,
Dietmar Ulrich
Publication year - 2021
Publication title -
diving and hyperbaric medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.389
H-Index - 20
eISSN - 2209-1491
pISSN - 1833-3516
DOI - 10.28920/dhm51.3.288-294
Subject(s) - medicine , radiation therapy , incidence (geometry) , perioperative , breast reconstruction , surgery , breast cancer , retrospective cohort study , logistic regression , complication , cancer , physics , optics
Radiotherapy reduces the risk of locoregional recurrence of breast cancer. As a side-effect, tissue can become hypocellular, hypovascular, and hypoxic and late radiation tissue injury can develop months or years later. Radiotherapy increases the risk of complications following secondary breast reconstruction. Hyperbaric oxygen treatment (HBOT) improves oxygenation of irradiated tissue and induces neovascularisation. This study evaluated whether the incidence of complications following secondary breast reconstruction after radiotherapy is decreased with perioperative HBOT.