Open AccessNecrostatin-1 prolongs latency to convulsion in mice exposed to high oxygen partial pressure
Author(s) -
Zhen-Biao Guan,
Yanyan Zhou,
Yi Cen,
Han-De Feng,
Wenwu Liu,
Hongjie Yi,
Hui Chen
Publication year - 2021
Publication title -
diving and hyperbaric medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.389
H-Index - 20
eISSN - 2209-1491
pISSN - 1833-3516
DOI - 10.28920/dhm51.2.134-139
Subject(s) - necroptosis , oxidative stress , pathogenesis , medicine , anesthesia , oxygen , oxygen toxicity , toxicity , convulsion , pharmacology , chemistry , apoptosis , programmed cell death , epilepsy , biochemistry , organic chemistry , lung , psychiatry
Exposure to very high oxygen partial pressure may cause central nervous system oxygen toxicity (CNS-OT). The role of necroptosis in the pathogenesis of CNS-OT is still unclear.