Open AccessNecrostatin-1 prolongs latency to convulsion in mice exposed to high oxygen partial pressure
Author(s) -
Zhenbiao Guan,
Yanyan Zhou,
Yi Cen,
Han-De Feng,
Wenwu Liu,
Hongjie Yi,
Hui Chen
Publication year - 2021
Publication title -
diving and hyperbaric medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.389
H-Index - 20
eISSN - 2209-1491
pISSN - 1833-3516
DOI - 10.28920/dhm51.2.134-139
Subject(s) - necroptosis , oxidative stress , pathogenesis , medicine , anesthesia , oxygen , convulsion , pharmacology , toxicity , oxygen toxicity , neuroprotection , immunology , chemistry , apoptosis , epilepsy , programmed cell death , biochemistry , organic chemistry , lung , psychiatry
Exposure to very high oxygen partial pressure may cause central nervous system oxygen toxicity (CNS-OT). The role of necroptosis in the pathogenesis of CNS-OT is still unclear.
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