Ongoing outbreak of hepatitis A in Nis, Serbia: a preliminary report

Hepatitis A is still a great problem in developing countries, especially those in which vaccination is not obligatory. It is well known that hepatitis A is associated with risk factors such as poor sanitation and inadequate hygiene. However, some investigations (e.g. in Spain and Greece) showed that the seroprevalence of antibodies against hepatitis A virus (HAV) in recent decades has decreased, especially in the younger adults, most likely due to improvements in living standards and hygienic conditions.