Open AccessEmergence and dissemination of multidrug resistant clones of Pseudomonas aeruginosa producing VIM-2 metallo-beta-lactamase in Belgium
Author(s) -
Ariane Deplano,
Hector Rodríguez-Villalobos,
Youri Glupczynski,
Pierre Bogaerts,
Daniël Allemeersch,
Alexandre Grimmelprez,
Georges Mascart,
L. Bergès,
Byl B,
C Laurent,
Marc Struelens
Publication year - 2007
Language(s) - English
Resource type - Journals
ISSN - 9999-1233
DOI - 10.2807/esw.12.03.03114-en
Subject(s) - pseudomonas aeruginosa , microbiology and biotechnology , biology , multiple drug resistance , beta lactamase , carbapenem , beta (programming language) , drug resistance , genetics , gene , bacteria , antibiotics , escherichia coli , computer science , programming language
Emergence of carbapenem-hydrolysing metallo-beta-lactamase (MBL) in Pseudomonas aeruginosa has been described worldwide. Infection with MBL-producing strains represents a therapeutic problem due to their resistance to all beta-lactams except monobactams. Several types of MBL enzymes have been identified in P. aeruginosa among which the VIM-type enzymes appear as the most prevalent in Europe with more than 12 allelic variants.