Robustness of measles immunity in parturient women in Gipuzkoa, Basque Country, Spain, in the post-vaccination era | Zendy

Gustavo Cilla | Zendy; E. Serrano-Bengoechea | Zendy; Diego Vicente | Zendy; Marisa Montes | Zendy; E Pérez-Trallero | Zendy

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Robustness of measles immunity in parturient women in Gipuzkoa, Basque Country, Spain, in the post-vaccination era

Author(s) -

Gustavo Cilla,

E. Serrano-Bengoechea,

Diego Vicente,

Marisa Montes,

E Pérez-Trallero

Publication year - 2007

Publication title -

eurosurveillance

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.766

H-Index - 104

eISSN - 1560-7917

pISSN - 1025-496X

DOI - 10.2807/esm.12.09.00732-en

Subject(s) - measles , medicine , vaccination , immunity , measles vaccine , passive immunity , immunization , immunology , pediatrics , herd immunity , measles virus , antibody , obstetrics , immune system

The infants of mothers with vaccine-induced immunity lose passive acquired measles antibodies earlier than infants of naturally infected mothers. This study included two cohorts of parturient women: one composed of women who gave birth in 1990 (end of the epidemic period), and another comprising women who gave birth in 2006 (after eight years without virus circulation). Immunoglobulin G (IgG) antibodies against measles (IgG-AM) were investigated by enzyme immunoassay in stored serum samples (-40°C). Measles-IgG titres of >400 mIU/mL were found in all 185 parturient women who gave birth in 1990, all with natural immunity. Of 185 women who gave birth in 2006, most of whom had vaccine-induced protection, measles-IgG were undetectable in 4.9% (

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