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Safety of multiple, submucosal inoculations of a live attenuated strangles vaccine in pregnant mares
Author(s) -
Reinhold B.,
Venner M.
Publication year - 2010
Publication title -
equine veterinary education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 31
eISSN - 2042-3292
pISSN - 0957-7734
DOI - 10.2746/095777309x479
Subject(s) - medicine , abortion , vaccination , streptococcus equi , inoculation , horse , attenuated vaccine , pregnancy , virology , immunology , biology , bacteria , virulence , paleontology , biochemistry , genetics , gene
Summary A live attenuated vaccine against Streptococcus equi was administered submucosally in the upper lip to 224 pregnant and healthy mares to evaluate its safety. After a primary immunisation the mares were inoculated every 3 months until foaling. As control group, 206 mares of the same breeding farm were administered the solvent of the vaccine submucosally. None of the 430 mares presented any clinical evidence of strangles and neither local nor systemic reactions to vaccination were noticed. There was no association between abortion and vaccination. Furthermore no case of S. equi infection was revealed at post mortem examinations of aborted foals.