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Antimicrobial therapy for difficult to identify and atypical pathogens
Author(s) -
Weese J. S.
Publication year - 2009
Publication title -
equine veterinary education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 31
eISSN - 2042-3292
pISSN - 0957-7734
DOI - 10.2746/095777308x334284
Subject(s) - lawsonia intracellularis , antimicrobial , organism , medicine , microbiology and biotechnology , fastidious organism , leptospira , biology , bacteria , serotype , paleontology , genetics
Summary Determination of appropriate antimicrobial therapy may be difficult for certain pathogens because of problems isolating the organism, inability to perform antimicrobial susceptibility testing, difficulty in obtaining a definitive diagnosis and lack of standard evidence‐based guidelines for treatment. Pathogens such as anaerobes, Borrelia burgdorferi, Anaplasma phagocytophilum, Leptospira spp., Lawsonia intracellularis, Mycoplasma spp. and Mycobacterium spp. present such challenges. While determination of optimal treatment may be more complicated than with other organisms, general recommendations have been made based on knowledge of the organism, data from other species, available in vitro data and clinical observation.