Open AccessPhysicochemical and biological activity studies on complexes of some transition elements with mixed ligands of glycine and urea
Author(s) -
Maher Ali Al-Maqtari,
Mohammed Kassem Othman Al-qadasy,
Yasmin M.S. Jamil,
Fathi M. Al-Azab,
Amani A. Al-Gaadbi
Publication year - 2018
Publication title -
eclética química
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.177
H-Index - 19
eISSN - 1678-4618
pISSN - 0100-4670
DOI - 10.26850/1678-4618eqj.v43.4.2018.p25-35
Subject(s) - chemistry , urea , molar conductivity , glycine , inorganic chemistry , transition metal , metal , solvent , coordination sphere , nuclear chemistry , octahedral molecular geometry , chloride , elemental analysis , organic chemistry , amino acid , catalysis , biochemistry
The reaction of urea (ur) and glycine (gly) with the metal ions Co(ΙΙ), Ni(ΙΙ) and Cu(ΙΙ) in ethanolic solution of 1M:1L1:1L2 molar ratio (where M= Co(II), Ni(II) and Cu(II), and L1 = urea L2 = glycine) led to the preparation of complexes of the general formula [M(ur)(gly)(H2O)2]Cl. Elemental microanalysis (CHN), molar conductivity measurements, IR,1HNMR, Mass and UV-VIS spectroscopic, and magnetic susceptibility measurements were used for the characterization of the compounds. Thermal analyses were used for the complexes degradation characterization. The complexes have an octahedral geometry and are of electrolytic nature in DMSO solvent with the absence of inner-sphere coordination of the chloride anion. An inhibition zone was observed for Ni-urea-glycine complex against Escherichia coli when the biological activity was considered.