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Features of cognitive dysfunction in patients with depressive disorder and cerebrovascular pathology
Author(s) -
Olga Prokhorova
Publication year - 2017
Publication title -
psihosomatična medicina ta zagalʹna praktika
Language(s) - English
Resource type - Journals
ISSN - 2519-8572
DOI - 10.26766/pmgp.v2i3.37
Subject(s) - executive dysfunction , dementia , cognition , pathognomonic , depression (economics) , disease , medicine , major depressive disorder , executive functions , cognitive decline , quality of life (healthcare) , psychiatry , cardiology , psychology , clinical psychology , neuropsychology , economics , macroeconomics , nursing
Background In recent years, there has been an increase in the number of elderly people, and at the same time the accumulation of mental and somatic diseases inherent in these age categories. Depression, dementia and cardiovascular disease continue to occupy leading positions. Executive dysfunction syndrome in patients with organic depressive disorder with cerebrovascular pathology is one of the pathognomonic features of violation of higher brain functions in subcortical ischemic depression, which is important for the prognosis of the disease, provision of timely medical care, development of preventive measures and improvement of patients' quality of life. Methods Using TMT and Strup tests, 138 patients with depressive disorder were screened for the purpose of detecting cognitive dysfunction. Results More pronounced cognitive dysfunction in the form of violation of the executive function, cognitive control, volume and distribution of attention was observed in patients with organic depressive disorder and signs of subcortical ischemia of the GM. Differences in the structure of violations of cognition are caused by zones of morphological defeat of the GM and the rupture of cortico-strial paths. Conclusion Thus, in patients with subcortical ischemic depression, there is a syndrome of executive dysfunction, which is the leading cause of subcortical ischemic dementia. Ability to develop and implement a comprehensive program for the recovery of cognitive dysfunction will improve the quality of life of patients.

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