Antiphospholipid syndrome and retinal vein occlusion in adults | Zendy

R. M. Maaroufi | Zendy; Rawaa Hamdi | Zendy; N. Jmili | Zendy; M. Ben Ghorbal | Zendy; Bel Hadj F. Hamida | Zendy; Touhami Mahjoub | Zendy

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Antiphospholipid syndrome and retinal vein occlusion in adults

Author(s) -

R. M. Maaroufi,

Rawaa Hamdi,

N. Jmili,

M. Ben Ghorbal,

Bel Hadj F. Hamida,

Touhami Mahjoub

Publication year - 2004

Publication title -

eastern mediterranean health journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.442

H-Index - 47

eISSN - 1687-1634

pISSN - 1020-3397

DOI - 10.26719/2004.10.4-5.627

Subject(s) - medicine , central retinal vein , retinal vein , antiphospholipid syndrome , fluorescein angiography , anticoagulant , retinal , ophthalmology , occlusion , lupus anticoagulant , cardiology , thrombosis

Antiphospholipid antibodies may play and important role in the pathogenesis of retinal vascular occlusions; investigated the prevalence among 33 patients with retinal vein and artery occlusions and 80 controls. Prevalence was 33% and 5% respectively. Ophthalmic examination and fluorescein angiography showed that occlusions were due to ischaemic events. The 11 patients were diagnosed with antiphospholipid syndrome:9 patients were treated successfully with laser photocoagulation and anticoagulant and anti-aggregant therapy. Two patients with antiphospholipid antibodies associated with resistance to activated protein C had unfavourable outcomes. Our results suggest a correlation between antiphospholipid syndrome and retinal vein occlusions; we recommend a systematic search for antiphospholipid antibodies in occlusions of unexplained origin and laser photocoagulation treatment and long-term oral anticoagulant and anti-aggregant therapy

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