z-logo
open-access-imgOpen Access
Quinine for chloroquine-resistant falciparum malaria in pregnant Sudanese women in the first trimester
Author(s) -
Ishaq Adam,
Idris Hm,
Elbashir Mi
Publication year - 2004
Publication title -
eastern mediterranean health journal/eastern mediterranean health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 47
eISSN - 1687-1634
pISSN - 1020-3397
DOI - 10.26719/2004.10.4-5.560
Subject(s) - quinine , medicine , malaria , pregnancy , chloroquine , obstetrics , plasmodium falciparum , gestational age , abortion , prospective cohort study , gestation , pediatrics , surgery , genetics , immunology , biology
A prospective clinical study in eastern Sudan described the efficacy and toxicity of quinine in early pregnancy in mothers with chloroquine-resistant falciparum malaria. Twenty-six pregnant Sudanese women in their first trimester [mean gestational age 8.5 weeks] were given quinine 10 mg/kg 3 times per day for 7 days and followed up every 2 weeks until delivery. One patient aborted [3.8%] and 2 patients [7.7%] experienced threatened abortion but delivered term babies. Recrudescence or re-infection was observed on day 21 in 1 patient. One baby died aged 6 months. There were no detectable congenital malformations, no auditory or visual defects or any other neurological deficits in the remaining infants at birth or 1 year later. Quinine may be safe in the first trimester of pregnancy

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here