Open AccessAntimicrobial resistance and plasmid profiles of urinary Escherichia coli isolates from Jordanian patients
Author(s) -
Asem A. Shehabi,
Azmi Mahafzah,
K Z Al Khalili
Publication year - 2004
Publication title -
eastern mediterranean health journal/eastern mediterranean health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 47
eISSN - 1687-1634
pISSN - 1020-3397
DOI - 10.26719/2004.10.3.322
Subject(s) - nalidixic acid , ampicillin , nitrofurantoin , tetracycline , microbiology and biotechnology , gentamicin , norfloxacin , cefuroxime , escherichia coli , plasmid , antibiotic resistance , antimicrobial , biology , medicine , antibiotics , ciprofloxacin , dna , biochemistry , genetics , gene
Weinvestigated antimicrobial resistance patterns and plasmid profiles of uropathogenic Escherichia coli isolates from inpatients and outpatients at Jordan University Hospital in 2000 and 2001. E. coli accounted for 32.4% and 37.4% of all isolates respectively. The lowest susceptibility was for ampicillin [11%], cotrimoxazole [23%] and tetracycline [26%]. The relative incidence of resistant isolates of E. coli to nalidixic acid, gentamicin, norfloxacin, cefuroxime and nitrofurantoin was significantly greater for inpatients than for outpatients [P< 0.05]. A large, transferable R-plasmid of 28 kb was found in most E. coli isolates [67%] that were resistant to at least ampicillin, cotrimoxazole and tetracycline. This R-plasmid reservoir may contribute to the spread of multiple antibiotic resistance in our Region