Ceftriaxone versus ampicillin/cloxacillin as antibiotic prophylaxis in elective caesarean section | Zendy

E. T. S. Ahmed | Zendy; O. A. Mirghani | Zendy; Abdul-Salam Gerais | Zendy; Ishag Adam | Zendy

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Ceftriaxone versus ampicillin/cloxacillin as antibiotic prophylaxis in elective caesarean section

Author(s) -

E. T. S. Ahmed,

O. A. Mirghani,

Abdul-Salam Gerais,

Ishag Adam

Publication year - 2004

Publication title -

eastern mediterranean health journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.442

H-Index - 47

eISSN - 1687-1634

pISSN - 1020-3397

DOI - 10.26719/2004.10.3.277

Subject(s) - cloxacillin , medicine , ceftriaxone , caesarean section , ampicillin , apgar score , anesthesia , antibiotics , surgery , pregnancy , birth weight , genetics , microbiology and biotechnology , biology

Wecarried out a prospective, r and omized, controlled clinical trial to evaluate the clinical efficacy of ceftriaxone and ampicillin/cloxacillin prophylaxis in decreasing the frequency of post-caesarean section infection-related morbidity. Two hundred patients randomly received either ceftriaxone [single dose] or ampicillin/cloxacillin [3 doses] intravenously at induction of anaesthesia. There was no statistical difference in incidence of endometritis [P = 0.34], wound infection [P = 0.44], or other febrile morbidity [P = 0.5]. Eleven babies had a low Apgar score [< 8] in the ceftriaxone group and 13 in the ampicillin/cloxacillin group [P = 0.82]. There were 2 perinatal deaths in each group. One dose of ceftriaxone was as effective as ampicillin/ cloxacillin in preventing post-caesarean section complications and is easier to administer

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