Prevalence of human papillomavirus in Mazandaran Province, Islamic Republic of Iran | Zendy

R Hamkar | Zendy; Talat MokhtariAzad | Zendy; Mahmood Mahmoodi | Zendy; S Seyedirashti | Zendy; Alberto Severini | Zendy; R Nategh | Zendy

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Prevalence of human papillomavirus in Mazandaran Province, Islamic Republic of Iran

Author(s) -

R Hamkar,

Talat MokhtariAzad,

Mahmood Mahmoodi,

S Seyedirashti,

Alberto Severini,

R Nategh

Publication year - 2002

Publication title -

eastern mediterranean health journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.442

H-Index - 47

eISSN - 1687-1634

pISSN - 1020-3397

DOI - 10.26719/2002.8.6.805

Subject(s) - human papillomavirus , cervical cancer , cervical carcinoma , medicine , biopsy , pathology , cancer

We report the prevalence of human papillomavirus [HPV] types in 100 cervical biopsy specimens in Mazandaran province. HPV DNA was detected in 78.6% of cervical carcinoma cases, 64.3% of dys/ metaplasia and 9% of normal cases. Significant correlation was found between the presence of HPV DNA and development of cervical carcinoma. HPV types 16 and 18 were detected in 60.6% of HPV-positive cervical carcinoma cases, whereas HPV31 and 33 were found in 21.2%, and HPV6 and 11 in 18.2%. Among HPV-positive dys/metaplasia cases, 55.6% were positive for HPV16 and 18, 22.3% for HPV6 and 11, and 11.1% for HPV31 and 33. Only HPV6 and 11 were detected in 4 [100%] normal biopsy specimens.

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