Screening for congenital hypothyroidism in the Islamic Republic of Iran: strategies, obstacles and future perspectives | Zendy

Arash Ordookhani | Zendy; Parvin Mirmiran | Zendy; R Hajipour | Zendy; Mehdi Hedayati | Zendy; Fereidoun Azizi | Zendy

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Screening for congenital hypothyroidism in the Islamic Republic of Iran: strategies, obstacles and future perspectives

Author(s) -

Arash Ordookhani,

Parvin Mirmiran,

R Hajipour,

Mehdi Hedayati,

Fereidoun Azizi

Publication year - 2002

Publication title -

eastern mediterranean health journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.442

H-Index - 47

eISSN - 1687-1634

pISSN - 1020-3397

DOI - 10.26719/2002.8.4-5.480

Subject(s) - levothyroxine , congenital hypothyroidism , islamic republic , medicine , pediatrics , cord blood , recall rate , cord , thyroid stimulating hormone , thyroid , obstetrics , surgery , islam , geography , archaeology , artificial intelligence , computer science

The operational feasibility of a congenital hypothyroidism [CH] screening programme was assessed. Cord blood spot specimens were collected at seven Teheran hospitals and within the Damavand District health network. Cord thyroid-stimulating hormone [TSH] levels > or = 20 mU/L were recalled and levothyroxine [L-T4] therapy was started immediately after diagnosis of CH. Of 20, 107 acceptable specimens, 22 neonates had CH [1: 914 births]. The recall rate was 1.3%. Screening coverage was 90% of live births. Of all cord samples, only 0.2% were unacceptable either because of delay in transportation or improper specimen collection. Median ages at the time of diagnosis and starting treatment were 12 and 8 days respectively. Screening for CH is feasible and a national screening programme is a necessity.

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