Open AccessHepatic fibrosis due to fascioliasis and/or schistosomiasis in Abis 1 village, Egypt
Author(s) -
L. M. Abou-Basha,
Aziza Ibrahim Salem,
Maher M. Osman,
S. El-Hefni,
A. Zaki
Publication year - 2000
Publication title -
eastern mediterranean health journal/eastern mediterranean health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 47
eISSN - 1687-1634
pISSN - 1020-3397
DOI - 10.26719/2000.6.5-6.870
Subject(s) - schistosomiasis , fibrosis , hepatic fibrosis , medicine , helminths , environmental health , immunology
An epidemiological study of fascioliasis and/or schistosomiasis was conducted in Abis 1 village. Stool specimens were collected from 2492 individuals and examined. Fascioliasis, alone or combined with schistosomiasis, was more prevalent among children aged between 5 years and 15 years than in adults. Serum procollagen III peptide [PIIIP]levels were determined as an indicator of active fibrosis, and liver histopathology and ultrasonography used as indicators of established fibrosis. PIIIP levels were significantly higher in children than in adults, and in mixed infections than in fascioliasis alone. In adults, fibrosis around granulomata detected by histopathology and grade 3 periportal fibrosis detected by sonography were encountered more frequently in dual than in single infections.