Open AccessAcanthosis nigricans, hyperinsulinaemia and risk factors for cardiovascular disease
Author(s) -
A Bener,
Gilles G. Lestringant,
B. L. Grégoire Nyomba,
Phillipe Frossard,
Hanane Saadi
Publication year - 2000
Publication title -
eastern mediterranean health journal/eastern mediterranean health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 47
eISSN - 1687-1634
pISSN - 1020-3397
DOI - 10.26719/2000.6.2-3.416
Subject(s) - acanthosis nigricans , medicine , hyperinsulinemia , endocrinology , triglyceride , diabetes mellitus , blood pressure , cholesterol , insulin , insulin resistance
We examined the association between acanthosis nigricans, hyperinsulinaemia and other risk factors for cardiovascular disease in patients from the United Arab Emirates. Height, weight and sitting blood pressure were recorded in 122 patients with acanthosis nigricans, and blood samples were obtained for measuring fasting cholesterol, high-density lipoprotein cholesterol, triglyceride and uric acid levels. In addition, a glucose tolerance test was performed and blood was sampled for insulin and glucose. Our results indicate that the patients with acanthosis nigricans had a high prevalence of abnormal glucose tolerance and hyperinsulinaemia. In addition, euglycaemic patients with hyperinsulinaemia had a cluster of risk factors for cardiovascular disease