Open AccessFollow-up of pregnant women with active cytomegalovirus infection
Author(s) -
al-Ali Hy,
Yasseen Sa,
Raof Ty
Publication year - 1999
Publication title -
eastern mediterranean health journal/eastern mediterranean health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 47
eISSN - 1687-1634
pISSN - 1020-3397
DOI - 10.26719/1999.5.5.949
Subject(s) - medicine , cytomegalovirus , microcephaly , serology , incidence (geometry) , cytomegalovirus infection , pediatrics , pregnancy , hydrocephalus , cord blood , obstetrics , immunology , herpesviridae , human cytomegalovirus , viral disease , virus , antibody , surgery , biology , physics , optics , genetics
Pregnant women [60]with and without serological evidence of active cytomegalovirus [CMV]infection were followed until delivery to detect the incidence and types of overt congenital CMV infection in neonates in Mosul, Iraq. Infection was diagnosed by the detection of CMV-IgM, using ELISA. CMV-IgM was detected in cord blood samples of six [10%]overtly sick infants [with different congenital malformations]born to mothers with active CMV infection. Central nervous system abnormalities were detected in all six cases [two with microcephaly and four with hydrocephaly]. Congenital CMV infection should be suspected in infants born with congenital malformations, especially those of the central nervous system. The detection of a significant number of hydrocephalus cases in our study is notable