Open AccessMajor histocompatibility class I antigens in the Lebanese population
Author(s) -
N. N. Salti,
Mark Shaya
Publication year - 2021
Publication title -
eastern mediterranean health journal/eastern mediterranean health journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.442
H-Index - 47
eISSN - 1687-1634
pISSN - 1020-3397
DOI - 10.26719/1997.3.1.101
Subject(s) - haplotype , major histocompatibility complex , histocompatibility , mongoloid , population , antigen , genetics , immunogenetics , biology , immunology , human leukocyte antigen , gene , allele , medicine , environmental health
Except for two reports on Lebanese immigrants, there have been no studies on the major histocompatibility [MHC] antigens in the Lebanese population. We describe the frequency and distribution of MHC class I antigens present in the A, B and C loci based on data obtained from 200 healthy unrelated individuals from different parts of Lebanon. The highest gene frequencies were as follows:A2 [24.8%], B35 [17.9%] and Cw4 [18.6%], making this haplotype the commonest. Comparison of genetic distances revealed a pattern closer to the Caucasoid population than to the Mongoloid, Oriental or Black populations