Major histocompatibility class I antigens in the Lebanese population | Zendy

N. N. Salti | Zendy; Mark Shaya | Zendy

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Major histocompatibility class I antigens in the Lebanese population

Author(s) -

N. N. Salti,

Mark Shaya

Publication year - 2021

Publication title -

eastern mediterranean health journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.442

H-Index - 47

eISSN - 1687-1634

pISSN - 1020-3397

DOI - 10.26719/1997.3.1.101

Subject(s) - haplotype , major histocompatibility complex , histocompatibility , mongoloid , population , antigen , genetics , immunogenetics , biology , immunology , human leukocyte antigen , gene , allele , medicine , environmental health

Except for two reports on Lebanese immigrants, there have been no studies on the major histocompatibility [MHC] antigens in the Lebanese population. We describe the frequency and distribution of MHC class I antigens present in the A, B and C loci based on data obtained from 200 healthy unrelated individuals from different parts of Lebanon. The highest gene frequencies were as follows:A2 [24.8%], B35 [17.9%] and Cw4 [18.6%], making this haplotype the commonest. Comparison of genetic distances revealed a pattern closer to the Caucasoid population than to the Mongoloid, Oriental or Black populations

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