Open AccessAnalysis of Microsatellite Instability in Colorectal Cancer and Precursor Lesions
Author(s) -
Yong Ge,
Hong Chen,
Jinku Zhang,
Jirui Sun
Publication year - 1970
Publication title -
proceedings of anticancer research
Language(s) - English
Resource type - Journals
eISSN - 2208-3553
pISSN - 2208-3545
DOI - 10.26689/par.v5i4.2314
Subject(s) - microsatellite instability , colorectal cancer , cancer , medicine , oncology , cancer research , microsatellite , biology , gene , genetics , allele
In many countries, colorectal cancer is one of the common cancers. It has been confirmed that microsatellite instability (MSI) is one of the most important molecular changes in colorectal cancer. As the recognized precursor lesions of colorectal cancer, adenomas and some polyps also have MSI phenomenon. This article analyzes the MSI of colorectal cancer and its closely related adenomas and polyps in domestic and foreign literature, and further discusses how to identify colorectal cancer at an early stage and the impact of MSI on the prognosis and treatment of colorectal cancer.