Preliminary study on Anti-inflammatory and Anti-tumor Effects of Gelatin - based on pH-responsive Drug-loaded Nanoparticles

 Gelatin as one kind of nano-drug carrier is a polysaccharide which can be absorbed after releasing all nano-drugs. Poly(ethylene glycol) as a polymer material that can modify nano-drugs is able to extend circulatory time of doxorubicin and aspirin, enhance stability and reduce toxicity. At precancerous, aspirin will be released slowly to resist inflammation. When tumor cell appears at a more advance stage, doxorubicin release from Gel to achieve anti-tumor effect. After all those steps, poly (ethylene glycol) could be expelled from body. In brief, the nano-drug that has doxorubicin and aspirin is able to prevent the growth of tumor cells and kill them when they appear more precisely.