Open AccessClinical efficacy of plasma exchange therapy for treatment of autoimmune bullous skin disease
Author(s) -
Xiaoxu Shi,
Lan-Ying Qin,
Jun Peng,
Zishen Zhao,
Haixiang Zhang
Publication year - 2019
Publication title -
journal of clinical and nursing research
Language(s) - English
Resource type - Journals
eISSN - 2208-3693
pISSN - 2208-3685
DOI - 10.26689/jcnr.v3i4.803
Subject(s) - medicine , incidence (geometry) , complication , autoimmune disease , gastroenterology , clinical efficacy , disease , dermatology , physics , optics
Objective: To investigate the clinical efficacy of plasma exchange therapy for autoimmune bullous skin disease. METHODS: Fifty patients with autoimmune bullous skin disease enrolled in our hospital from January 2018 to January 2019 were selected. The patients were grouped by treatment method: 25 control group patients were given conventional hormone therapy, while 25 experimental group patients were treated with plasma exchange therapy; efficacy of treatment was compared between two groups of patients. RESULTS: Initial dose, maximum dose, and cumulative dose of glucocorticoids were lower in experimental group patients than those in control group (P 0.05). Conclusion: The application of plasma exchange therapy was effective for treatment of autoimmune bullous skin disease. It could reduce dosage amount of glucocorticoids and incidence of complications; its application can be promoted.