Open AccessBioengineered Acellular Vessel Implantation in a Patient with Chronic Limb-Threatening Ischemia: A Case Report and Discussion of Implications for Trauma
Author(s) -
Alexis L Lauria,
Joseph White,
Alexander J Kersey,
Paul W. White,
Todd E. Rasmussen
Publication year - 2021
Publication title -
journal of endovascular resuscitation and trauma management
Language(s) - English
Resource type - Journals
eISSN - 2003-539X
pISSN - 2002-7567
DOI - 10.26676/jevtm.v5i2.197
Subject(s) - medicine , ischemia , electrical conduit , surgery , limb ischemia , vascular graft , vein , implant , cardiology , engineering , mechanical engineering
The ideal conduit for vascular reconstruction is one that can be obtained “off the shelf” and demonstrates long-term patency, tissue incorporation and resistance to infection. Currently available conduits, such as autologous vein and synthetic grafts, are limited in one or more of these areas. The Human Acellular Vessel (HAV), a bioengineered, acellular blood vessel, can be obtained “off the shelf” and has shown promise in each of these properties. We describe a case in which the HAV was utilized for open bypass reconstruction in a patient with chronic limb-threatening ischemia who lacked alternative reconstructive options. The case is followed by a discussion of potential broader applications of this novel implant, specifically in the management of vascular trauma.