Open AccessChemical profiles and antioxidant properties of Bruguiera gymnorrhiza fruit extracts from Central Sulawesi, Indonesia
Author(s) -
Putut Har Riyadi,
Wendy Alexander Tanod,
Didit Kustantio Dewanto,
Vivi Endar Herawati,
Edi Susanto,
Siti Aisiah
Publication year - 2021
Publication title -
food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.218
H-Index - 7
ISSN - 2550-2166
DOI - 10.26656/fr.2017.5(s3).007
Subject(s) - bruguiera , dpph , chemistry , antioxidant , nutraceutical , botany , traditional medicine , food science , biology , biochemistry , mangrove , medicine , ecology
Bruguiera gymnorrhiza is one of the mangrove species that a source of antioxidants.Antioxidant substances are able to protect cells from oxidative stress and other relateddiseases. This study aimed to evaluate the chemical profiles, predicted biological activity,and antioxidant activity of the B. gymnoriza fruit extracts. The research methods includedsampling, extraction (maceration with MeOH:DCM), identification of chemical profiles(GCMS spectra analysis), assaying for computational analysis (PASS server andADMET), antioxidants (DPPH radical scavenging), and total phenolic content (FolinCiocalteu). Bruguiera gymnorrhiza fruits was collected from Central Sulawesi, Indonesia.The chemical profiles detected in the B. gymnorrhiza fruit extracts, namelyisopimaradiene (64.20%); 4-(2-Aminopropyl) phenol (19.06%); dimethylaminodimethylphosphene oxide (9.40%); 3-amino-2-benzylbutanoic acid (5.46%); and 1,4-dideuteriooctane (1.89%). PASS server analysis showed that the five compounds detectedfrom B. gymnorrhiza fruit have the potential as an NF-E2-related factor (Nrf2) stimulantand oxygen scavenger. The ADMET analysis results indicated that B. gymnorrhiza fruitscould be developed as folk medicine and nutraceutical products.