Open AccessCherubism: Case Report and Review of Literature
Author(s) -
Sabah Nuri Mizel,
Ali Fakhree Alzubaidee
Publication year - 2021
Publication title -
maǧallaẗ diyālá al-ṭibbiyyaẗ/maǧallaẗ diyālá al-ṭibbiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2617-8982
pISSN - 2219-9764
DOI - 10.26505/djm.21015940308
Subject(s) - cherubism , maxilla , mandible (arthropod mouthpart) , medicine , lesion , dentistry , pathology , giant cell , biology , botany , genus
Cherubism is an autosomal dominant, very rare benign fibro-osseous lesion, with an estimation of only 300 cases have been reported worldwide. Cherubism is characterized clinically by bilateral symmetrical self-limiting jaw enlargement starts in the childhood or early teens.Mandible is mostly affected although maxilla and zygomatic bones may be involved but to a lower extent), and is associated with tooth displacement and severe malocclusion. Histopathologically, it is indistinguishable from giant cell lesions therefore the clinical manifestations of the disease remain the Gold Stone. Keywords: Cherubism, mandible, maxilla, bilateral palatal swelling