z-logo
open-access-imgOpen Access
Sex of the Fetus can be Associated with Placental Pathologies in Premature Deliveries
Author(s) -
Wasan Munim,
Niran Kamel,
Alaa Raheem Kareem,
Mustafa Rasool Hussein Aal-Saleh,
Mohammed Luay Subhi,
Sarah Abdulkareem Ali Al-Dujaili
Publication year - 2020
Publication title -
maǧallaẗ diyālá al-ṭibbiyyaẗ/maǧallaẗ diyālá al-ṭibbiyyaẗ
Language(s) - English
Resource type - Journals
eISSN - 2617-8982
pISSN - 2219-9764
DOI - 10.26505/djm.19025370514
Subject(s) - fetus , pathological , placenta , medicine , gestation , gestational age , obstetrics , pregnancy , birth weight , in utero , physiology , pathology , biology , genetics
Background: There are many pregnancy complications that are significantly associated with the gender of the fetus; one of them is preterm labour, which is an important obstetric problem that may lead to many perinatal morbidity and mortality. Objective: To find out whether there is a relation between the findings of placental pathology of premature deliveries and gender difference. Patients and Methods: Fifty deliveries before a 32 week gestational age. Obstetrical, and placental histological findings have been compared among all males (n=25), and females (n=25) premature neonates. Results: The male premature fetus had distribution rate in maternal age, gestation age at the time of delivery, placental weight, and feto-placental weight-ratio in females, but a higher birth-weight centile ([55.09±11.3] versus [43.09±8.2]). Histopathology of the placenta found no significant association of fetal-sex with acute inflammatory lesions (p=0.09), intra-placental vascular pathological findings, or utero-placental vascular pathology. However, the chronic inflammatory lesion showed a higher pathological score in male fetuses than in the females (p=0.01). Conclusion: Premature deliveries with less than thirty-two weeks, the male fetal-sex had higher placental pathological lesions, suggesting maternal immunological responses towards the invading trophoblasts. The immunological background of these pathological lesions needs further studies. Keywords: Male fetal sex, placental pathology, premature delivery

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here