Open AccessFACILE FABRICATION OF COPPER OXIDE NANOPARTICLES FOR ANTIMICROBIAL ACTIVITY
Author(s) -
Md. Ashraful Haque,
Md. Kaium Hossain,
Md. Ashraful Islam Molla,
Mithun Sarker,
Shaikat Chandra Dey,
Md. Ashaduzzaman
Publication year - 2021
Publication title -
journal cleanwas
Language(s) - English
Resource type - Journals
eISSN - 2521-0912
pISSN - 2521-0513
DOI - 10.26480/jcleanwas.01.2021.27.30
Subject(s) - copper , fourier transform infrared spectroscopy , antimicrobial , nanoparticle , materials science , copper oxide , scanning electron microscope , oxide , monoclinic crystal system , nuclear chemistry , chemical engineering , nanotechnology , chemistry , organic chemistry , metallurgy , composite material , crystal structure , engineering
Copper Oxide nanoparticles (NPs) have shown great acceptance in the antimicrobial application owing to their low toxicity and high surface to charge ratio. In this study, copper oxide NPs (represented as S-1, S-2 and S-3) were prepared by a simple and cost-effective thermal approach in three different environments. Fabricated NPs were characterized using x-ray diffraction (XRD), scanning electron microscopy (SEM), ultraviolet-visible (UV-Vis) spectroscopy and Fourier transform infrared spectroscopy (FTIR) technique. The XRD patterns revealed that the synthesized S-2 was of pure Cu2O phase while S-3 was composed of monoclinic CuO with a small quantity of Cu2O. More importantly, synthesized copper oxide NPs were used to evaluate the antimicrobial activity against three types of gram-negative bacteria namely Salmonella typhi, SK4 and E. coli (two strains). Although the NPs produced from the S-1 approach did not show encouraging results, the copper oxide NPs from S-2 and S-3 had shown enhanced antimicrobial activity. The successful antimicrobial activity of S-2 and S-3 can be related to the release of Cu+ and Cu2+ ions into the surrounding environment, which is responsible for the breaking of the cell wall membrane and ultimately causes bacterial cell disruption. The synthesized copper oxide NPs via thermal approach will be good candidates for biomedical applications.