Open AccessPotential (2,2-azinobis (3-ethylbenzatiazolin) -6 -sulfonic acid) reducing and anti-elastase of ethanol extract of KEMANGI leaves (Ocimumbasilicum L.) and Eugenol
Author(s) -
Jenny Jenny,
Ermi Girsang,
Ali Napiah Nasution,
Sukirman Lie
Publication year - 2019
Publication title -
journal of inventions in biomedical and pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 2456-818X
DOI - 10.26452/jibps.v4i4.1432
Subject(s) - eugenol , chemistry , antioxidant , abts , ethanol , elastase , methyl eugenol , camellia oleifera , traditional medicine , antimicrobial , food science , biochemistry , dpph , botany , organic chemistry , biology , enzyme , medicine , pest analysis , tephritidae
Aging is a complex process characterized by a progressive decrease in the physiological functions of the body, including the skin, followed by dysfunction, and death. Kemangi leaves (Ocimumbasilicum L.) have been used empirically and are scientifically proven to have a variety of pharmacological activities, including analgesic, sedative, anti-inflammatory, antioxidant, antiaging, antimicrobial, antifungal, antiviral and contains chemical compounds eugenol, linalool, β-Caryophyllene. The purpose of this study was to determine the antioxidant activity and anti-elastase of the ethanol extract of kemangi leaves and eugenol. In this study, antioxidant activity was tested by ABTS reduction method (2,2-Azinobis (3-ethylbenzatiazolin) -6-sulfonic acid) and elastase inhibition tested by ethanol extract of kemangi leaves with a comparison of eugenol compounds. The results of ABTS reduction antioxidant activity based on IC50 Eugenol value of 2.09 μg / ml and ethanol extract of kemangi leaves of 18.27 μg / ml, anti-elastase from Eugenol at 37.49 μg / ml and ethanol extract of kemangi leaves at 43.02 μ / ml.