Open AccessThe impact of iron deficiency anemia on histomorphological features of placenta and the newborn infants.
Author(s) -
Rafah Hady lateef Al Mamouri,
Aaya Hamid Al hakeem
Publication year - 2018
Publication title -
international journal of research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-7538
DOI - 10.26452/ijrps.v9ispl1.1347
Subject(s) - placenta , anemia , fetus , pregnancy , iron deficiency anemia , medicine , thickening , obstetrics , hypoxia (environmental) , physiology , biology , chemistry , oxygen , genetics , organic chemistry , polymer science
Iron deficiency anemia during pregnancy ismutual heamatological disorder that happens in pregnancy,it affects maternal blood, leading to hypoxia,which cause changes in the structure of the placenta. Aim of study to explore the changes occurres bothin gross morphology and in histology of the placenta in anemic mothers. Methods: A fifty placentas were taken from mothers (full term) delivered at hospital constituted the material for thepresent study. Full term placentawas collected with case history and investigated after delivery of fetus. Two cm pieces were removed from both anemic and normalgroup of placenta fixed in 10% formalin and used for processing and staining.The microscopic study revealed histomorphological abnormalities as increased capillaries per villas,thickening of capillary basement membrane, trophoblastic basementmembrane,cytotrophoplastic proliferation, syncytial knots and fibrosis. All these changes occurred maintaining sufficient efficiency of placenta,to fulfill demand of oxgen in the fetus.